Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699604 | 0.85 | MAPT (0.47) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7698114 | 0.84 | MAPT (0.48) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7695132 | 0.84 | MAPT (0.49) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7699148 | 0.83 | MAPT (0.48) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7699046 | 0.82 | POLB (0.45) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7695160 | 0.80 | MAPT (0.41) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7694375 | 0.80 | HSD17B10 (0.40) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7695678 | 0.80 | CHRNB2 (0.49) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7699090 | 0.80 | MAPT (0.40) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL7698104 | 0.79 | MAPT (0.51) | RAB9AMEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |