Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698664 | 1.00 | RIPK1 (0.42) | RIPK1SLC1A1PTGS1PTGS2DPP4 | |
| SCHEMBL7698662 | 1.00 | RIPK1 (0.42) | RIPK1SLC1A1PTGS1PTGS2DPP4 | |
| SCHEMBL5813461 | 0.76 | LDHA (0.51) | RIPK1PTGS1PTGS2DPP4PIN1 | |
| SCHEMBL31067929 | 0.74 | TBXAS1 (0.44) | RIPK1PTGS1PTGS2DPP4PIN1 | |
| SCHEMBL6003686 | 0.74 | TBXAS1 (0.44) | RIPK1PTGS1PTGS2DPP4PIN1 | |
| SCHEMBL6005325 | 0.74 | TBXAS1 (0.44) | RIPK1PTGS1PTGS2DPP4PIN1 | |
| SCHEMBL6003677 | 0.74 | TBXAS1 (0.44) | RIPK1PTGS1PTGS2DPP4PIN1 | |
| SCHEMBL7230282 | 0.73 | KDM6B (0.61) | RIPK1DPP4PIN1MAOAMAOB | |
| SCHEMBL7711037 | 0.73 | KDM6B (0.61) | RIPK1DPP4PIN1MAOAMAOB | |
| SCHEMBL7429475 | 0.72 | POLB (0.49) | PPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |