Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARG | Q86W56 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007108 | 0.87 | GBA1 (0.56) | KMT2AGBA1ALDH1A1MEN1CYP2C9 | |
| SCHEMBL7699722 | 0.83 | KMT2A (0.68) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28113177 | 0.83 | KMT2A (0.67) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4390035 | 0.82 | KMT2A (0.60) | KMT2AGBA1ALDH1A1MEN1CYP2C9 | |
| SCHEMBL4390037 | 0.82 | KMT2A (0.60) | KMT2AGBA1ALDH1A1MEN1CYP2C9 | |
| SCHEMBL7698041 | 0.80 | KMT2A (0.67) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8396377 | 0.80 | GBA1 (0.83) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7886816 | 0.80 | GBA1 (0.83) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23052369 | 0.79 | KMT2A (0.62) | KMT2AGBA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29183291 | 0.79 | ALDH1A1 (0.64) | KMT2AALDH1A1SMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |