Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390037 | 1.00 | KMT2A (0.60) | KMT2AALDH1A1MEN1CYP2C9GBA1 | |
| SCHEMBL4007108 | 0.84 | GBA1 (0.56) | KMT2AALDH1A1MEN1CYP2C9GBA1 | |
| SCHEMBL13590685 | 0.83 | ACACB (0.70) | KMT2AALDH1A1MEN1CYP2C9GBA1 | |
| SCHEMBL7698803 | 0.82 | KMT2A (0.62) | KMT2AALDH1A1MEN1CYP2C9GBA1 | |
| SCHEMBL4400809 | 0.82 | GBA1 (0.66) | KMT2AALDH1A1MEN1CYP2C9GBA1 | |
| SCHEMBL4400806 | 0.82 | GBA1 (0.66) | KMT2AALDH1A1MEN1CYP2C9GBA1 | |
| SCHEMBL4397778 | 0.81 | MEN1 (0.68) | KMT2AALDH1A1MEN1CYP2C9POLB | |
| SCHEMBL4397776 | 0.81 | MEN1 (0.68) | KMT2AALDH1A1MEN1CYP2C9POLB | |
| SCHEMBL7698607 | 0.80 | KMT2A (0.58) | KMT2AALDH1A1MEN1CYP2C9POLB | |
| SCHEMBL4396124 | 0.80 | PDK1 (0.54) | KMT2AALDH1A1MEN1CYP2C9GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | KMT2A 1754/4885ALDH1A1 169/4885MEN1 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.