Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 12/20 | 0.54 |
| ▸ | XDH | P47989 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985355 | 0.83 | CA1 (0.49) | GPR84XDHCA1CA2CA9 | |
| SCHEMBL4128821 | 0.78 | XDH (0.56) | GPR84XDHBCHETRPC3TRPC4 | |
| SCHEMBL7618338 | 0.72 | XDH (0.55) | GPR84XDHBCHETRPC3TRPC4 | |
| SCHEMBL10576480 | 0.72 | XDH (0.45) | GPR84XDHBCHETRPC3TRPC4 | |
| SCHEMBL9655166 | 0.70 | GPR84 (0.58) | GPR84XDH | |
| SCHEMBL6685725 | 0.69 | GPR84 (0.51) | GPR84 | |
| SCHEMBL4384740 | 0.69 | XDH (0.67) | GPR84XDHBCHETRPC3TRPC4 | |
| SCHEMBL9288448 | 0.69 | XDH (0.60) | GPR84XDH | |
| SCHEMBL9288451 | 0.69 | XDH (0.47) | GPR84XDHBCHETRPC3TRPC4 | |
| SCHEMBL20117490 | 0.68 | GPR84 (0.56) | GPR84XDHBCHETRPC3TRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005911-B1 | ANALGESIC 6-ACYLAMINOTETRAHYDRO-1,3,5-TRIAZINE-2,4-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | claimed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | claimed |
| EP-0005911-A1 | Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-12-12 | — | — | EP | claimed |
| US-6335339-B1 | PREVENTING HEPATITIS B INFECTION WITH VIRICIDE | SCRIPTGEN PHARMACEUTICALS, INC. | 2002-01-01 | — | — | US | disclosed |
| EP-1053230-A1 | TRIAZINE ANTIVIRAL COMPOUNDS | Scriptgen Pharmaceuticals, Inc. (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999036410-A9 | TRIAZINE ANTIVIRAL COMPOUNDS | SCRIPTGEN PHARM INC (US) | 1999-09-30 | — | — | WO | disclosed |
| WO-1999036410-A1 | TRIAZINE ANTIVIRAL COMPOUNDS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| EP-0005911-B1 | ANALGESIC 6-ACYLAMINOTETRAHYDRO-1,3,5-TRIAZINE-2,4-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | disclosed |
| EP-0005911-B1 | ANALGESIC 6-ACYLAMINOTETRAHYDRO-1,3,5-TRIAZINE-2,4-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | disclosed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | disclosed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | disclosed |
| EP-0005911-A1 | Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-12-12 | — | — | EP | disclosed |
| EP-0005911-A1 | Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-12-12 | — | — | EP | disclosed |