SCHEMBL7699059

SCHEMBL7699059

C=CCc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.55
GABRB2 P47870 1/20 0.55
GPR35 Q9HC97 7/20 0.50
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
XDH P47989 1/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
TTR P02766 1/20 0.43
CYP1A2 P05177 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28001850 0.89 GABRA1 (0.50) GABRA1GABRB2GPR35XDHALDH1A1
SCHEMBL11288152 0.89 GPR35 (0.54) GABRA1GABRB2GPR35CA12CA1
SCHEMBL28539274 0.89 GABRA1 (0.50) GABRA1GABRB2GPR35CA12CA1
SCHEMBL10729189 0.85 GABRA1 (0.65) GABRA1GABRB2ALDH1A1KDM4ECYP1A2
SCHEMBL25337785 0.82 TNKS (0.65) GABRA1GABRB2XDHALDH1A1KDM4E
SCHEMBL29519288 0.82 TNKS (0.65) GABRA1GABRB2XDHALDH1A1KDM4E
SCHEMBL8733637 0.81 XDH (0.58) GABRA1GABRB2GPR35CA12CA1
SCHEMBL30141409 0.78 GABRA1 (0.74) GABRA1GABRB2MEN1MAPTKMT2A
SCHEMBL25337239 0.78 GABRA1 (0.74) GABRA1GABRB2MEN1MAPTKMT2A
SCHEMBL10881818 0.78 GPR35 (0.59) GPR35CRHBPCRHR2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53127831-A None JP disclosed
CN-112661649-B 2,6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2023-01-10 CN disclosed
CN-112661649-A 2, 6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2021-04-16 CN disclosed
CN-101823967-A Synthesis process of 2, 6-dinitro-4-alkylphenol NANTONG ZHENGYAN PIGMENT CHEMICAL CO LTD 2010-09-08 CN disclosed
CN-101823967-A Synthesis process of 2, 6-dinitro-4-alkylphenol NANTONG ZHENGYAN PIGMENT CHEMICAL CO LTD 2010-09-08 CN disclosed
CN-101823967-A Synthesis process of 2, 6-dinitro-4-alkylphenol NANTONG ZHENGYAN PIGMENT CHEMICAL CO LTD 2010-09-08 CN disclosed
US-6339177-B1 TO INHIBIT OLEFIN POLYMERIZATION BY DEACTIVATING RADICALS THAT LEAD TO POLYMERIZATION SEA LION TECHNOLOGY, INC. 2002-01-15 US disclosed
JP-S53127831-A NOVEL MICROBICIDE LION CORP 1978-11-08 JP disclosed