SCHEMBL8733637

SCHEMBL8733637

C=CCc1ccc(O)c([N+](=O)[O-])c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.58
MAPT P10636 5/20 0.56
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 3/20 0.56
GABRA1 P14867 3/20 0.56
GABRB2 P47870 3/20 0.56
NPSR1 Q6W5P4 2/20 0.56
HPGD P15428 2/20 0.56
MEN1 O00255 2/20 0.56
GAA P10253 2/20 0.56
CNR1 P21554 2/20 0.56
CNR2 P34972 2/20 0.56
KMT2A Q03164 2/20 0.56
ALDH2 P05091 1/20 0.56
AKR1B1 P15121 1/20 0.56
PPARG P37231 1/20 0.56
PPARD Q03181 1/20 0.56
POLB P06746 2/20 0.52
MAPK1 P28482 2/20 0.51
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603437 0.87 XDH (0.58) XDHMAPTALDH1A1KDM4EGABRA1
SCHEMBL2772403 0.86 ALDH5A1 (0.59) MAPTALDH1A1KDM4ENPSR1HPGD
SCHEMBL25337785 0.84 TNKS (0.65) XDHMAPTALDH1A1KDM4EGABRA1
SCHEMBL29519288 0.84 TNKS (0.65) XDHMAPTALDH1A1KDM4EGABRA1
SCHEMBL7699059 0.81 GABRA1 (0.55) XDHMAPTALDH1A1KDM4EGABRA1
SCHEMBL3529585 0.81 POLB (0.56) MAPTALDH1A1KDM4ENPSR1HPGD
SCHEMBL11002820 0.80 MAPK1 (0.60) MAPTALDH1A1KDM4ENPSR1HPGD
SCHEMBL69585 0.80 SNCA (0.62) MAPTALDH1A1KDM4ENPSR1HPGD
SCHEMBL30477507 0.80 SNCA (0.62) MAPTALDH1A1KDM4ENPSR1HPGD
SCHEMBL9511426 0.80 VCAM1 (0.51) ALDH1A1KDM4EHPGDAKR1B1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637294-B1 POLYMERIZATION INHIBITOR FOR VINYL AROMATICS UNIROYAL CHEM CO INC (US) 1998-07-29 EP disclosed