Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ADH5 | P11766 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143444 | 0.92 | KDM4D (0.35) | CCR3CTSSCTSVCTSLCTSB | |
| SCHEMBL7141841 | 0.89 | KDM4D (0.35) | CCR3CTSSCTSVCTSLCTSB | |
| SCHEMBL7145195 | 0.85 | KDM4D (0.34) | CCR3CTSSCTSVCTSLCTSB | |
| SCHEMBL7138171 | 0.78 | KDM4D (0.37) | CCR3CTSSCTSVCTSLCTSB | |
| SCHEMBL7703665 | 0.76 | VCP (0.36) | CCR3 | |
| SCHEMBL7138021 | 0.75 | KDM4D (0.35) | CCR3ABL1HSD11B1 | |
| SCHEMBL7703659 | 0.74 | UCHL1 (0.36) | CCR3 | |
| SCHEMBL7144093 | 0.74 | KDM4D (0.36) | CCR3ABL1CCKBRHSD11B1 | |
| SCHEMBL7141955 | 0.73 | KDM4D (0.36) | CCR3ABL1CCKBR | |
| SCHEMBL7146597 | 0.71 | ADH5 (0.41) | ABL1ADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224174-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029011-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |