Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699217 | 0.79 | MAPT (0.36) | MAPTLMNAALDH1A1TSHRKMT2A | |
| SCHEMBL7694348 | 0.79 | HTR2C (0.38) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7698082 | 0.78 | AVPR1A (0.57) | AVPR2AVPR1AMAPTLMNAALDH1A1 | |
| SCHEMBL7695160 | 0.78 | MAPT (0.41) | MAPTLMNAALDH1A1TSHRKMT2A | |
| SCHEMBL7703801 | 0.78 | L3MBTL1 (0.49) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7698990 | 0.78 | HTR2C (0.43) | LMNAALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL7698850 | 0.74 | GPBAR1 (0.39) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL7699604 | 0.73 | MAPT (0.47) | MAPTLMNAALDH1A1TSHRKMT2A | |
| SCHEMBL7699623 | 0.73 | AVPR2 (0.46) | AVPR2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL7698114 | 0.72 | MAPT (0.48) | MAPTLMNAALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |