Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698666 | 0.92 | L3MBTL1 (0.44) | L3MBTL1PDE10AMAPTHPGDRAB9A | |
| SCHEMBL7698990 | 0.87 | HTR2C (0.43) | HTR2CABL1BCRHPGDRAB9A | |
| SCHEMBL7703801 | 0.87 | L3MBTL1 (0.49) | ABL1BCRL3MBTL1MAPTTSHR | |
| SCHEMBL7699217 | 0.87 | MAPT (0.36) | HTR2CABL1BCRL3MBTL1MAPT | |
| SCHEMBL7695160 | 0.82 | MAPT (0.41) | MAPTHPGDRAB9ATSHRNPC1 | |
| SCHEMBL7700016 | 0.80 | IKBKB (0.42) | L3MBTL1MAPTHPGDTSHRMEN1 | |
| SCHEMBL7699994 | 0.79 | ATM (0.47) | L3MBTL1MAPTTSHRALDH1A1MEN1 | |
| SCHEMBL7699803 | 0.79 | NPC1 (0.44) | L3MBTL1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL7696382 | 0.79 | L3MBTL1 (0.58) | L3MBTL1MAPTTSHRALDH1A1HSD17B10 | |
| SCHEMBL7699423 | 0.79 | AVPR2 (0.52) | MAPTRAB9ATSHRNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |