Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699803 | 0.92 | NPC1 (0.44) | ACHEHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7694348 | 0.87 | HTR2C (0.38) | HTR2CHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7703801 | 0.86 | L3MBTL1 (0.49) | ALDH1A1TP53MEN1KMT2ATDP1 | |
| SCHEMBL7699217 | 0.86 | MAPT (0.36) | HTR2CHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7695160 | 0.81 | MAPT (0.41) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7698666 | 0.79 | L3MBTL1 (0.44) | HPGDALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7699994 | 0.79 | ATM (0.47) | ALDH1A1SMN1; SMN2LMNAHTTTP53 | |
| SCHEMBL7696382 | 0.78 | L3MBTL1 (0.58) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL7699423 | 0.78 | AVPR2 (0.52) | ALDH1A1SMN1; SMN2LMNAHTTNPC1 | |
| SCHEMBL7698850 | 0.77 | GPBAR1 (0.39) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |