Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699861 | 0.87 | TK1 (0.45) | — | |
| SCHEMBL4084059 | 0.77 | B4GALT1 (0.35) | TDP1MEN1KMT2AP2RY12P2RY2 | |
| SCHEMBL6880850 | 0.77 | TAS1R3 (0.49) | MEN1KMT2ANT5E | |
| SCHEMBL6875722 | 0.76 | TYMP (0.41) | TDP1 | |
| SCHEMBL17198388 | 0.75 | TDP1 (0.46) | TDP1KMT2AP2RY12P2RY2P2RY6 | |
| SCHEMBL30428170 | 0.75 | SLC28A1 (0.51) | TDP1P2RY12P2RY2P2RY6P2RY4 | |
| SCHEMBL7624341 | 0.72 | SLC28A1 (0.57) | P2RY12P2RY2P2RY6P2RY4 | |
| SCHEMBL10431697 | 0.71 | P2RY2 (0.47) | TDP1P2RY12P2RY2P2RY6P2RY4 | |
| SCHEMBL7715642 | 0.71 | SLC28A1 (0.50) | P2RY12P2RY2P2RY6P2RY4 | |
| SCHEMBL7715645 | 0.71 | SLC28A1 (0.47) | P2RY12P2RY2NT5EP2RY6P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403566-B1 | CONFORMATIONALLY LOCKED; ANTIVIRAL, ANTICANCER, STABILITY TO CELLULAR NUCLEASES AND STRONG BINDING AFFINITY TO NUCLEIC ACID TARGETS. | ICN PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | disclosed |