Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699900 | 0.91 | KLK7 (0.43) | KLK7KLK5GPR119KMT2APRSS1 | |
| SCHEMBL31486428 | 0.87 | KLK7 (0.49) | KLK7P2RX7KLK5MEN1KMT2A | |
| SCHEMBL8669568 | 0.87 | KLK7 (0.49) | KLK7P2RX7KLK5MEN1KMT2A | |
| SCHEMBL5065670 | 0.87 | KLK7 (0.49) | KLK7P2RX7KLK5MEN1KMT2A | |
| SCHEMBL1371651 | 0.84 | PPARG (0.41) | KLK7P2RX7KLK5 | |
| SCHEMBL1371650 | 0.84 | PPARG (0.41) | KLK7P2RX7KLK5 | |
| SCHEMBL2185219 | 0.83 | PPARG (0.45) | P2RX7HTTMEN1KMT2A | |
| SCHEMBL8211740 | 0.82 | ROCK2 (0.38) | MMP13ROCK2P2RX7HTT | |
| SCHEMBL5204187 | 0.82 | OPRK1 (0.44) | KLK7P2RX7KLK5 | |
| SCHEMBL27840720 | 0.80 | P2RX7 (0.41) | P2RX7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |