Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489209 | 0.81 | KMT2A (0.41) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL9118274 | 0.78 | HPGD (0.45) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL27286555 | 0.73 | KMT2A (0.34) | KMT2AALDH1A1MAPTHPGDGAA | |
| SCHEMBL8488374 | 0.73 | CES2 (0.45) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8492580 | 0.72 | RAB9A (0.35) | ALDH1A1MAPTHPGDGAALMNA | |
| SCHEMBL8492842 | 0.71 | ALDH1A1 (0.40) | KMT2AALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL8493033 | 0.69 | KMT2A (0.34) | KMT2AMEN1LMNA | |
| SCHEMBL8494848 | 0.69 | HPD (0.57) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7700496 | 0.69 | KMT2A (0.52) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8493489 | 0.68 | SLC6A2 (0.39) | ALDH1A1GAALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588357-B1 | Isoxazoles derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |