Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27286555 | 0.91 | KMT2A (0.34) | KMT2APDK2KDM4EALDH1A1HPGD | |
| SCHEMBL8488374 | 0.88 | CES2 (0.45) | KMT2AHPDKDM4EUSP2ALDH1A1 | |
| SCHEMBL8492842 | 0.86 | ALDH1A1 (0.40) | KMT2AKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL8488762 | 0.85 | HPD (0.44) | PDK2PDE2AGPR119HPDKDM4E | |
| SCHEMBL8494848 | 0.83 | HPD (0.57) | KMT2AHPDALDH1A1CYP2C19MEN1 | |
| SCHEMBL8492580 | 0.82 | RAB9A (0.35) | KDM4EALDH1A1HPGDCYP2C19LMNA | |
| SCHEMBL9195406 | 0.82 | HPGD (0.37) | GPR119KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8489240 | 0.81 | GPR119 (0.38) | KMT2APDK2GPR119ALDH1A1CYP2C19 | |
| SCHEMBL7700518 | 0.81 | KMT2A (0.44) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL8493033 | 0.80 | KMT2A (0.34) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066439-C | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGROCHIMIE (GB) | 2001-05-30 | — | — | CN | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| CN-1037058-C | Herbicide composition and use thereof | RHONE POULENC AGRICULTURE (GB) | 1998-01-21 | — | — | CN | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| CN-1141294-A | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-01-29 | — | — | CN | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |