SCHEMBL7700776

SCHEMBL7700776

COC1(OC)C=CC(C(c2ccccc2)(c2ccccc2)C(O)COCCOCCOCCOCCOCCO)=CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30513670 0.76 KMT2A (0.38) NR1H2NR1H3
SCHEMBL2821675 0.76 KMT2A (0.38) NR1H2NR1H3
SCHEMBL6572295 0.76
SCHEMBL4300671 0.73 KIF11 (0.42) NR1H2NR1H3
SCHEMBL4194075 0.71 LMNA (0.40) NR1H2NR1H3
SCHEMBL8135345 0.70 CHRM3 (0.35)
SCHEMBL22368 0.69 TSHR (0.31)
SCHEMBL3238217 0.68 ALDH1A1 (0.43)
SCHEMBL6037704 0.67 KIF11 (0.40)
SCHEMBL2205525 0.60 MEN1 (0.33) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208234-A1 POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS BIO-RAD LABORATORIES, INC. (US) 2002-05-29 EP disclosed
US-6348583-B1 NUCLEOBASE CONTAINING POLYTHIOETHERS SYNTHESIZED ON POLYETHYLENE GLYCOL, SUCCINIC ANHYDRIDE AND PROPYLAMINE MODIFIED GLASS; NUCLEIC ACID MIMETICS BIO-RAD LABORATORIES, INC. 2002-02-19 US disclosed
WO-2001016365-A1 POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS BIO-RAD LABORATORIES, INC. (US) 2001-03-08 WO disclosed