Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 5/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | GRK3 | P35626 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698091 | 0.87 | HTT (0.46) | KDM4ELMNA | |
| SCHEMBL7698726 | 0.86 | LMNA (0.47) | EPHX2ROCK2PRKD3LMNAIKBKB | |
| SCHEMBL7703284 | 0.86 | EPHX2 (0.46) | EPHX2CNR1CNR2PTGESHSD17B13 | |
| SCHEMBL7696114 | 0.86 | EPHX2 (0.44) | EPHX2CNR1CNR2PTGESHSD17B13 | |
| SCHEMBL7699810 | 0.84 | EPHX2 (0.45) | EPHX2CNR1CNR2PTGESBTK | |
| SCHEMBL7693979 | 0.83 | IKBKB (0.42) | KDM4EIKBKB | |
| SCHEMBL7695359 | 0.82 | EPHX2 (0.44) | EPHX2CNR1CNR2PTGESHSD17B13 | |
| SCHEMBL7699627 | 0.81 | IKBKB (0.40) | KDM4ESMN1; SMN2IKBKB | |
| SCHEMBL7695326 | 0.81 | IKBKB (0.40) | KDM4ESMN1; SMN2IKBKB | |
| SCHEMBL7699232 | 0.80 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |