Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692558 | 0.84 | RAB9A (0.63) | LMNANR1H4EPHX2RAB9AHDAC1 | |
| SCHEMBL7701997 | 0.78 | POLB (0.57) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10606216 | 0.73 | EPHX2 (0.65) | LMNAALDH1A1NR1H4EPHX2RAB9A | |
| SCHEMBL130789 | 0.72 | SMN1; SMN2 (0.53) | NR1H4EPHX2RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL15942950 | 0.71 | RAB9A (0.65) | LMNAALDH1A1NR1H4EPHX2RAB9A | |
| SCHEMBL10625366 | 0.71 | NR1H4 (0.59) | LMNANR1H4EPHX2RAB9AMEN1 | |
| SCHEMBL4984479 | 0.71 | HDAC1 (0.48) | LMNAALDH1A1NR1H4EPHX2RAB9A | |
| SCHEMBL26042662 | 0.70 | EPHX2 (0.61) | LMNANR1H4EPHX2RAB9AHDAC1 | |
| SCHEMBL10871615 | 0.70 | HDAC1 (0.52) | LMNAALDH1A1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL450084 | 0.70 | RAB9A (0.85) | LMNAALDH1A1NR1H4EPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |