Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 4/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704952 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2GAAESRRGESRRBMEN1 | |
| SCHEMBL7700674 | 0.83 | RAB9A (0.42) | RAB9AMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL7695335 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2EPHX2MAPTALDH1A1LMNA | |
| SCHEMBL7699627 | 0.77 | IKBKB (0.40) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7699962 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2GAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7695145 | 0.76 | IKBKB (0.45) | NR1H4MAPTALDH1A1LMNAHPGD | |
| SCHEMBL30106351 | 0.76 | TRPV1 (0.49) | SMN1; SMN2GAAMEN1KMT2ANPC1 | |
| SCHEMBL7701939 | 0.75 | HSP90AA1 (0.47) | SMN1; SMN2GAAMEN1KMT2ANPC1 | |
| SCHEMBL7693990 | 0.75 | IKBKB (0.53) | MEN1KMT2ANPC1RAB9ANR1H4 | |
| SCHEMBL7693979 | 0.75 | IKBKB (0.42) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |