Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48731 | 1.00 | POLB (0.64) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| Dimethylamine SCHEMBL7701402 | 0.92 | POLB (0.56) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL9620534 | 0.91 | HSD17B10 (0.52) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| Azobenzene SCHEMBL9551792 | 0.84 | ALDH1A1 (0.67) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL27094281 | 0.82 | POLB (0.69) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL11811491 | 0.78 | CYP2D6 (0.64) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL6774400 | 0.78 | POLB (0.53) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL5881591 | 0.78 | CA2 (0.70) | POLBCYP2D6ALDH1A1HSD17B10MAPT | |
| SCHEMBL6563719 | 0.78 | POLB (1.00) | POLBCYP2D6ALDH1A1TDP1MAPT | |
| SCHEMBL408153 | 0.78 | POLB (1.00) | POLBCYP2D6ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383170-A1 | FLEXIBLE AND SMART WOOD WITH RESPONSIVE FUNCTION, PREPARATION METHOD THEREOF AND ACTUATOR | NANJING FORESTRY UNIVERSITY (CN) | 2024-11-21 | — | — | US | claimed |
| JP-5216222-A | — | — | None | — | — | JP | disclosed |
| CN-108273478-B | Formaldehyde removal composition and product | 李怀玉 | 2021-03-02 | — | — | CN | disclosed |
| US-8129406-B2 | Nonpeptide inhibitors of matrix metalloproteinases | SOUTHERN RESEARCH INSTITUTE (US) | 2012-03-06 | — | — | US | disclosed |
| EP-1735274-B1 | NONPEPTIDE INHIBITORS OF MATRIX METALLOPROTEINASES | SOUTHERN RES INST (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20080312329-A1 | Nonpeptide Inhibitors of Matrix Metalloproteinases | SOUTHERN RESEARCH INSTITUTE (US) | 2008-12-18 | — | — | US | disclosed |
| US-20080287466-A1 | 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | ADAMS JERRY LEROY | 2008-11-20 | — | — | US | disclosed |
| US-7427623-B2 | 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof | SMITHKLINE BEECHAM CORPORATION (US) | 2008-09-23 | — | — | US | disclosed |
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050004142-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2005-01-06 | — | — | US | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| EP-0510983-B1 | Positive resist composition | NIPPON ZEON CO (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5376497-A | Good sensitivity, rate of residual film and resolution | NIPPON ZEON CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| JP-H05216222-A | POSITIVE TYPE PHOTORESIST COMPOSITION | FUJI PHOTO FILM CO LTD | 1993-08-27 | — | — | JP | disclosed |
| EP-0510983-A1 | Positive resist composition | NIPPON ZEON CO., LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-4339240-A | TIME-TEMPERATURE INDICATORS | ALLIED CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4152153-A | DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4076529-A | PHOTOGRAPHIC DIFFUSION TRANSFER FILMS, PROCESSES AND COMPOSITIONS WITH COLOR MOIETY RELEASING COMPOUND | EASTMAN KODAK COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-3993638-A | Ballasted p-sulfonamidophenols capable of releasing a non-heterocyclic azo dye | EASTMAN KODAK COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3981859-A | Silicone-compatible azo dyestuffs | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312329-A1 | Nonpeptide Inhibitors of Matrix Metalloproteinases | MMP1, MMP3, MMP10 | POLB 1070/4885CYP2D6 1883/4885ALDH1A1 918/4885 |
| US-20050004142-A1 | Chemical compounds | TIE1, KDR, TEK | POLB 928/4885CYP2D6 2559/4885ALDH1A1 906/4885 |
| US-20080287466-A1 | 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | TIE1, TEK, KDR | POLB 1327/4885CYP2D6 1693/4885ALDH1A1 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.