SCHEMBL9620534

SCHEMBL9620534

O=S(=O)(Cl)c1ccc(N=Nc2ccc(S(=O)(=O)Cl)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA12 O43570 6/20 0.50
CA2 P00918 6/20 0.50
CA9 Q16790 6/20 0.50
POLB P06746 3/20 0.50
CYP2D6 P10635 1/20 0.50
CA7 P43166 1/20 0.48
PTGS2 P35354 5/20 0.44
PTGS1 P23219 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
LMNA P02545 1/20 0.41
RPS6KA3 P51812 2/20 0.41
CYP2C9 P11712 2/20 0.41
PHLPP2 Q6ZVD8 2/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48731 0.91 POLB (0.64) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL48732 0.91 POLB (0.64) HSD17B10ALDH1A1TDP1CA12CA2
Dimethylamine SCHEMBL7701402 0.84 POLB (0.56) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL15704429 0.84 CA2 (0.69) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL42343 0.84 NPC1 (0.69) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL42344 0.84 NPC1 (0.69) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL22567048 0.84 CA12 (0.43) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL651902 0.83 ALDH1A1 (0.71) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL11921694 0.82 ALDH1A1 (0.50) HSD17B10ALDH1A1TDP1CA12CA2
SCHEMBL10767433 0.81 CA12 (0.43) HSD17B10ALDH1A1TDP1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233152-B1 PHOTOGRAPHIC MATERIAL FOR THE SILVER-DYE BLEACHING PROCESS ILFORD AG (CH) 1992-01-02 EP disclosed
US-4803151-A Photographic material for the silver dye bleach process comprising an AZO dye, capable of laking, in gelatine CIBA-GEIGY AG (CH) 1989-02-07 US disclosed
US-3981859-A Silicone-compatible azo dyestuffs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-09-21 US disclosed