Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696582 | 0.84 | DYRK1A (0.57) | MEN1KMT2ALRRK2ADORA2AADORA1 | |
| SCHEMBL7701581 | 0.77 | DYRK1A (0.55) | MEN1KMT2ALRRK2ADORA2AADORA1 | |
| SCHEMBL8991158 | 0.77 | KMT2A (0.49) | MEN1KMT2ARAB9ANPC1LRRK2 | |
| SCHEMBL7701231 | 0.73 | DYRK1A (0.55) | LRRK2ADORA2AADORA1DYRK1AKDM4E | |
| SCHEMBL8991180 | 0.73 | LRRK2 (0.43) | MEN1KMT2ARAB9ANPC1LRRK2 | |
| SCHEMBL7701233 | 0.72 | DYRK1A (0.51) | LRRK2ADORA2AADORA1DYRK1AKDM4E | |
| SCHEMBL8991102 | 0.71 | DYRK1A (0.56) | MEN1KMT2ARAB9ANPC1LRRK2 | |
| SCHEMBL8991348 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2ARAB9ANPC1LRRK2 | |
| SCHEMBL7700915 | 0.69 | DYRK1A (0.50) | KMT2ALRRK2ADORA2AADORA1DYRK1A | |
| SCHEMBL8991276 | 0.68 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |