Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693910 | 0.83 | NPC1 (0.45) | SMN1; SMN2KDM4EHSD17B10NPC1HTT | |
| SCHEMBL7693979 | 0.83 | IKBKB (0.42) | ALDH1A1POLBKDM4ETP53HSD17B10 | |
| SCHEMBL7699627 | 0.81 | IKBKB (0.40) | SMN1; SMN2ALDH1A1POLBKDM4ETP53 | |
| SCHEMBL7698726 | 0.81 | LMNA (0.47) | POLBLMNARAB9AGSK3B | |
| SCHEMBL7695326 | 0.81 | IKBKB (0.40) | SMN1; SMN2ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL7702181 | 0.81 | MEN1 (0.44) | SMN1; SMN2ALDH1A1KDM4ETP53KMT2A | |
| SCHEMBL7696445 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1POLBTSHRKDM4E | |
| SCHEMBL7700006 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL7699216 | 0.78 | IKBKB (0.41) | ALDH1A1KDM4ETP53HSD17B10HPGD | |
| SCHEMBL7695157 | 0.78 | IKBKB (0.48) | ALDH1A1KDM4ETP53HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |