SCHEMBL7702290

SCHEMBL7702290

CNC(=O)C(=O)C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351018 0.78 KDM5B (0.37) ALDH1A1
SCHEMBL20919868 0.75 ALDH1A1 (0.36) ALDH1A1
SCHEMBL6986174 0.73 CYP1A2 (0.35)
SCHEMBL7752566 0.73 EPHX1 (0.37)
SCHEMBL18909085 0.73
SCHEMBL2239024 0.71
SCHEMBL348208 0.71 TSHR (0.40) ALDH1A1
SCHEMBL10402594 0.71 EPHX1 (0.41)
SCHEMBL13245283 0.71 TSHR (0.39) TDP1ALDH1A1
SCHEMBL24133269 0.69 MEN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11048167-B2 Positive photosensitive resin composition, patterned cured film production method, patterned cured film, and electronic component HD MICROSYSTEMS, LTD. (JP) 2021-06-29 US disclosed
US-20180074403-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNED CURED FILM PRODUCTION METHOD, PATTERNED CURED FILM, AND ELECTRONIC COMPONENT HD MICROSYSTEMS, LTD. (JP) 2018-03-15 US disclosed
US-9790197-B2 Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) 2017-10-17 US disclosed
US-20160326108-A1 PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS BRISTOL MYERS SQUIBB CO (US) 2016-11-10 US disclosed
US-9458171-B2 Pyrrolidinyl sulfone RORγ modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2016-10-04 US disclosed
US-20150191483-A1 PYRROLIDINYL SULFONE RORGAMMA MODULATORS BRISTOL-MYERS SQUIBB COMPANY 2015-07-09 US disclosed
US-7592419-B2 Macrocyclic inhibitors of hepatitis C virus NS3-serine protease SCHERING CORPORATION (US) 2009-09-22 US disclosed
US-6348612-B1 FORM COMPLEXES USED AS CATALYSTS FOR ENANTIOSELECTIVE REACTIONS SUCH AS ASYMMETRIC HYDROGENATIONS, ENANTIOSELECTIVE HYDROGEN DISPLACEMENTS, ALLYLIC SUBSTITUTION REACTIONS ROCHE VITAMINS INC. 2002-02-19 US disclosed
EP-0798289-B1 Alpha-Iminocarboxylic acid derivative HOFFMANN LA ROCHE (CH) 2001-03-07 EP disclosed
EP-0864576-A1 Novel amidophospine-phosphinite derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP disclosed
US-5710322-A Optically active iminocarboxylic acid derivatives HOFFMANN-LA ROCHE INC. (US) 1998-01-20 US disclosed
EP-0798289-A1 Alpha-Iminocarboxylic acid derivative F. HOFFMANN-LA ROCHE AG (CH) 1997-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326108-A1 PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS RORC, RORB, RORA TDP1 2490/4885ALDH1A1 1327/4885
US-20150191483-A1 PYRROLIDINYL SULFONE RORGAMMA MODULATORS RORC, RORB, RORA TDP1 2482/4885ALDH1A1 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.