Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 10/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 8/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.38 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702471 | 0.84 | F2 (0.42) | KLKB1MAP4K1KLK1F2PRSS1 | |
| SCHEMBL6437972 | 0.79 | F2 (0.49) | KLKB1MAP4K1KLK1F2PRSS1 | |
| SCHEMBL4704282 | 0.79 | CHRM1 (0.44) | — | |
| SCHEMBL4705390 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL4704760 | 0.75 | CHRM1 (0.48) | KCNH2 | |
| SCHEMBL7431443 | 0.74 | KLKB1 (0.44) | KLKB1MAP4K1KLK1ROCK1C1S | |
| SCHEMBL4702059 | 0.71 | OPRD1 (0.41) | — | |
| SCHEMBL15153143 | 0.69 | CHRM1 (0.46) | — | |
| SCHEMBL15153161 | 0.69 | CHRM1 (0.46) | — | |
| SCHEMBL3738889 | 0.69 | CTSD (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |