Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700374 | 0.93 | ALDH1A1 (0.32) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7704553 | 0.87 | IKBKB (0.34) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7702691 | 0.74 | HPGD (0.43) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7696153 | 0.73 | ALDH1A1 (0.47) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7699801 | 0.73 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7700999 | 0.71 | MAPT (0.48) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158580 | 0.71 | ALDH1A1 (0.69) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7701068 | 0.71 | ALDH1A1 (0.69) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7701500 | 0.70 | GPBAR1 (0.47) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7700372 | 0.68 | HPGD (0.41) | KMT2AALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |