Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456760 | 0.69 | POLB (0.42) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL28299251 | 0.67 | ALDH1A1 (0.56) | KMT2AGPR3ALDH1A1KDM4EMAPT | |
| SCHEMBL3067398 | 0.67 | ALDH1A1 (0.68) | KMT2AGPR3MEN1ALDH1A1KDM4E | |
| SCHEMBL9596955 | 0.67 | GPR3 (0.44) | KMT2AGPR3MEN1ALDH1A1KDM4E | |
| SCHEMBL29289272 | 0.67 | HSD17B10 (0.45) | KMT2AGPR3MEN1ALDH1A1KDM4E | |
| SCHEMBL1415779 | 0.67 | KMT2A (0.58) | KMT2AGPR3MEN1ALDH1A1KDM4E | |
| SCHEMBL13014673 | 0.65 | KDM4E (0.50) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL26533624 | 0.65 | GPR3 (0.39) | KMT2AGPR3ALDH1A1KDM4EMAPT | |
| SCHEMBL28279288 | 0.65 | MAP2K3 (0.53) | GPR3ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL8573192 | 0.65 | SMN1; SMN2 (0.52) | KMT2AGPR3ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |
| EP-0915851-A1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998002421-A1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 1998-01-22 | — | — | WO | disclosed |