Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12622681 | 0.81 | LMNA (0.53) | SMN1; SMN2ARALDH1A1MAPK1NPC1 | |
| SCHEMBL10931456 | 0.81 | MAPK1 (0.59) | SMN1; SMN2ARALDH1A1HTTMAPK1 | |
| SCHEMBL8247256 | 0.81 | MAPT (0.54) | SMN1; SMN2ARALDH1A1HIF1ATDP1 | |
| SCHEMBL8624905 | 0.80 | PTGS2 (0.51) | SMN1; SMN2ARALDH1A1LMNAMAPT | |
| SCHEMBL11169076 | 0.80 | MAPT (0.49) | SMN1; SMN2ARALDH1A1HTTNPC1 | |
| SCHEMBL12622683 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HIF1ATDP1VDR | |
| SCHEMBL934362 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2ARALDH1A1MAPT | |
| SCHEMBL421801 | 0.79 | ALOX15 (0.61) | SMN1; SMN2ALDH1A1HTTNPC1LMNA | |
| SCHEMBL7708595 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ARALDH1A1HTTHIF1A | |
| SCHEMBL506467 | 0.79 | PPARG (0.53) | SMN1; SMN2ARALDH1A1HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |