Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATF4 | P18848 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841275 | 0.95 | MAPT (0.48) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL11003513 | 0.84 | SMN1; SMN2 (0.51) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10636684 | 0.84 | PTGS2 (0.48) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10917930 | 0.84 | MAP4K4 (0.50) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10636693 | 0.84 | MAPT (0.49) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10406787 | 0.84 | PTGS2 (0.48) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10931456 | 0.83 | MAPK1 (0.59) | ALDH1A1ELANESMN1; SMN2AR | |
| SCHEMBL8247256 | 0.83 | MAPT (0.54) | L3MBTL1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12622681 | 0.83 | LMNA (0.53) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11165052 | 0.83 | PTGS2 (0.47) | PTGS2L3MBTL1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102584551-A | Synthetic method of triazolone intermediate 1-(4-chlorinated phenoxyl)-1-chlorinated pinacoline | YANCHENG LIMIN CHEMICAL CO LTD | 2012-07-18 | — | — | CN | claimed |
| EP-0124013-B1 | PROCESS FOR THE PREPARATION OF OXIRANES | BAYER AG (DE) | 1988-07-13 | — | — | EP | claimed |
| EP-0124013-A2 | Process for the preparation of oxiranes | BAYER AG (DE) | 1984-11-07 | — | — | EP | claimed |
| US-20220400678-A1 | OXIME ETHER COMPOUND AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
| CN-114890951-A | Synthesis method of Ganbaosu | 山东汉峰新材料科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| US-20220162156-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | Cellix Bio Provate Limited (IN) | 2022-05-26 | — | — | US | disclosed |
| WO-2020254102-A1 | PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND A FATTY CONSTITUENT | HENKEL AG & CO. KGAA (DE) | 2020-12-24 | — | — | WO | disclosed |
| US-20160271133-A1 | Methods of Treating Multiple Myeloma and Resistant Cancers | PROLEXYS PHARMACEUTICALS INC (US) | 2016-09-22 | — | — | US | disclosed |
| CN-102584551-A | Synthetic method of triazolone intermediate 1-(4-chlorinated phenoxyl)-1-chlorinated pinacoline | YANCHENG LIMIN CHEMICAL CO LTD | 2012-07-18 | — | — | CN | disclosed |
| US-20110092489-A1 | 3-Aryl-Substituted Quinazolones, and Uses Thereof | Prolexys Pharmaceuticals ,Inc. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20100048594-A1 | USE OF CYTOHESIN INHIBITORS FOR CHEMICALLY INDUCING LONGEVITY | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT (DE) | 2010-02-25 | — | — | US | disclosed |
| EP-0040345-A1 | 1-Hydroxyethyl-azole derivatives, process for their preparation and their use in the regulation of plant growth and as fungicides | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0037591-A1 | Phenoxy-pyrimidinyl alkanols, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0035697-A1 | 3,3-Dimethyl-1-phenoxy-2-butanols, process for their preparation and their use as intermediates | BAYER AG (DE) | 1981-09-16 | — | — | EP | disclosed |
| EP-0028755-A1 | Plant growth regulating agent, its preparation and its use | BAYER AG (DE) | 1981-05-20 | — | — | EP | disclosed |
| US-4262000-A | CONTAINING ETHER AND KETONE OR HYDROXYL GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | disclosed |
| EP-0016974-A1 | 3-Substituted pyridine derivatives, process for their preparation, their use as fungicides, and intermediates | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
| EP-0001399-A1 | Phenoxy-pyridinyl-alcanols, process for their preparation and their use as fungicides | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |
| US-3987180-A | 1-PROPYL-IMIDAZOLYL ANTIMYCOTIC COMPOSITIONS AND METHODS OF TREATING MYCOSES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3940415-A | FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271133-A1 | Methods of Treating Multiple Myeloma and Resistant Cancers | MCL1, SLC11A2, MEN1 | PTGS2 2604/4885L3MBTL1 745/4885MEN1 3/4885 |
| US-20110092489-A1 | 3-Aryl-Substituted Quinazolones, and Uses Thereof | MKI67, MCL1, HCCS | PTGS2 1158/4885L3MBTL1 2892/4885MEN1 2337/4885 |
| US-20220162156-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | SI, SLC10A2, F5 | PTGS2 1404/4885L3MBTL1 4880/4885MEN1 3871/4885 |
| US-20100048594-A1 | USE OF CYTOHESIN INHIBITORS FOR CHEMICALLY INDUCING LONGEVITY | IGFBP1, IGFBP2, IGFBP5 | PTGS2 1124/4885L3MBTL1 366/4885MEN1 604/4885 |
| US-20220400678-A1 | OXIME ETHER COMPOUND AND APPLICATION THEREOF | CYP2E1, GALE, OGFOD1 | PTGS2 657/4885L3MBTL1 3034/4885MEN1 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.