Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | WHR1 | P49842 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702282 | 0.92 | ALOX15 (0.43) | ABHD6PDE3BPDE3AKMT2ASMN1; SMN2 | |
| SCHEMBL8169053 | 0.81 | PLA2G2A (0.47) | ABHD6KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL7702922 | 0.80 | PDE3B (0.41) | PDE3BPDE3AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7703696 | 0.76 | KDM4E (0.43) | ABHD6KMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL7698174 | 0.74 | PDE3B (0.47) | PDE3BPDE3AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7701145 | 0.74 | GABRA1 (0.46) | ABHD6KMT2ASMN1; SMN2KDM4EPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL7697990 | 0.73 | ABHD6 (0.39) | ABHD6 | |
| SCHEMBL7703348 | 0.71 | PLA2G2A (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7698330 | 0.70 | PLA2G2A (0.45) | KDM4EPOLBALDH1A1GABRA1GABRG2 | |
| SCHEMBL7702301 | 0.70 | ALOX15 (0.41) | PDE3BPDE3AKMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |