Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158637 | 0.84 | HPGD (0.45) | MAPTALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL7699326 | 0.84 | IKBKB (0.47) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL7699962 | 0.80 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL7701097 | 0.78 | KDM4E (0.47) | MAPTALDH1A1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL7704952 | 0.77 | SMN1; SMN2 (0.44) | MAPTALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL7695247 | 0.77 | EPHX2 (0.54) | MAPTALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL7699894 | 0.76 | IKBKB (0.54) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL29158719 | 0.76 | CD274 (0.49) | ALDH1A1EPHX2 | |
| SCHEMBL7698920 | 0.76 | GFER (0.52) | MAPTALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL7696445 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1SMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |