Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991084 | 0.87 | LRRK2 (0.42) | LRRK2KDM4EALDH1A1LMNAGLA | |
| SCHEMBL7701687 | 0.87 | LRRK2 (0.54) | LRRK2KDM4EALDH1A1LMNAGLA | |
| SCHEMBL8991180 | 0.81 | LRRK2 (0.43) | LRRK2KDM4EALDH1A1LMNAGLA | |
| SCHEMBL8991290 | 0.79 | RET (0.33) | RETMEN1NPC1NR2F2RAB9A | |
| SCHEMBL8991298 | 0.76 | RET (0.33) | RET | |
| SCHEMBL8991178 | 0.76 | RET (0.31) | RETMEN1NPC1NR2F2RAB9A | |
| SCHEMBL7703241 | 0.76 | DYRK1A (0.56) | LRRK2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7701250 | 0.76 | ACACB (0.33) | ALDH1A1 | |
| SCHEMBL8991316 | 0.76 | ALDH1A1 (0.55) | LRRK2KDM4EALDH1A1LMNAGLA | |
| SCHEMBL8991158 | 0.74 | KMT2A (0.49) | LRRK2KDM4EALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |