SCHEMBL7703745

SCHEMBL7703745

CC(Cc1ccc(CC(C)OO)cc1)OO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.43
SLC6A2 P23975 3/20 0.43
PTGS1 P23219 3/20 0.42
PTGS2 P35354 3/20 0.42
LMNA P02545 2/20 0.42
CYP2C9 P11712 2/20 0.42
AKR1C3 P42330 2/20 0.42
CXCR1 P25024 2/20 0.42
CXCR2 P25025 2/20 0.42
ESR1 P03372 2/20 0.42
ALB P02768 1/20 0.42
ALOX5 P09917 1/20 0.42
RARB P10826 1/20 0.42
ADRB3 P13945 1/20 0.42
NFKB1 P19838 1/20 0.42
HTR2A P28223 1/20 0.42
NR1I3 Q14994 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
CXCL8 P10145 1/20 0.42
LDHA P00338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175395 0.93 SRR (0.42) TAAR1SLC6A2PTGS1PTGS2LMNA
SCHEMBL9497974 0.91 TAAR1 (0.57) TAAR1SLC6A2ESR1ADRB3ESR2
SCHEMBL9898783 0.91 TRPA1 (0.38) TAAR1SLC6A2PTGS1PTGS2LMNA
SCHEMBL9771947 0.90 TAAR1 (0.54) TAAR1SLC6A2HTR2ATSHRTRPA1
SCHEMBL9492753 0.89 IDO1 (0.48) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL9899581 0.87 SIGMAR1 (0.46) LMNASIGMAR1
SCHEMBL9179601 0.85 ALDH1A1 (0.41) LMNAADRB3TRPA1
SCHEMBL9171681 0.84 HTR2A (0.48) SLC6A2PTGS1PTGS2LMNACYP2C9
SCHEMBL28334721 0.84 ALOX15 (0.32) TAAR1SLC6A2PTGS2LMNACYP2C9
SCHEMBL9170102 0.84 IDO1 (0.44) PTGS1PTGS2LMNACYP2C9AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609737-B1 Process for producing a halogenated butyl rubber BAYER INC (CA) 2000-06-07 EP claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 EP claimed
EP-1003900-B1 A PROCESS FOR THE PREPARATION OF A TERTIARY PERESTER AKZO NOBEL NV (NL) 2002-10-02 EP disclosed
US-6268523-B1 CONTACTING ACYL COMPOUND WITH TERTIARY HYDROPEROXIDE IN PRESENCE OF ENZYME CATALYST TO PRODUCE PERESTER AKZO NOBEL NV (NL) 2001-07-31 US disclosed
EP-1003900-A1 A PROCESS FOR THE PREPARATION OF A TERTIARY PERESTER Akzo Nobel N.V. (NL) 2000-05-31 EP disclosed
WO-1999005305-A1 A PROCESS FOR THE PREPARATION OF A TERTIARY PERESTER AKZO NOBEL N.V. (NL) 1999-02-04 WO disclosed
EP-0267759-B1 OXIDATION PROCESS OF AROMATIC COMPOUNDS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-4825007-A Oxidation process of aromatic compounds KUREHA KAGAKU KOGYO K.K. (JP) 1989-04-25 US disclosed
EP-0267759-A2 Oxidation process of aromatic compounds KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-05-18 EP disclosed
US-4129704-A Polymerization of vinyl monomers employing a diperoxyester mixture composition prepared by reacting dihydroperoxide and peroxyester forming carbonyl compounds PENNWALT CORPORATION (US) 1978-12-12 US disclosed
US-4097408-A FROM DIHYDOPEROXIDE AND CARBONYL COMPOUND, POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1978-06-27 US disclosed