Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 9/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL7699753 | 0.86 | LMNA (0.35) | LMNANPSR1MAPTMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL7702813 | 0.85 | ACHE (0.33) | ACHEPSMD14NSD2HSP90AA1CFTR | |
| Trifluoromethanesulfonic Acid SCHEMBL7702814 | 0.82 | ACHE (0.35) | ACHEPSMD14NSD2HSP90AA1CFTR | |
| Trifluoromethanesulfonic Acid SCHEMBL2996949 | 0.76 | ACHE (0.42) | LMNAACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL7702492 | 0.74 | KCNH2 (0.35) | ACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL7703830 | 0.74 | ACHE (0.34) | ACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL7697990 | 0.74 | ABHD6 (0.39) | ACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL38665301 | 0.73 | MAPT (0.39) | NPSR1MAPTACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL5705540 | 0.73 | MAPT (0.39) | NPSR1MAPTACHEKCNH2 | |
| SCHEMBL7702301 | 0.73 | ALOX15 (0.41) | NPSR1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |