Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 3/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016348 | 0.75 | KDM4E (0.51) | LTA4HKMT2A | |
| SCHEMBL6016364 | 0.72 | ALDH1A1 (0.47) | MAPK1KMT2APOLB | |
| SCHEMBL6016539 | 0.71 | KDM4E (0.53) | MKNK1KMT2APOLB | |
| SCHEMBL6016487 | 0.71 | MEN1 (0.46) | MAPK1KMT2A | |
| SCHEMBL4965391 | 0.70 | LTA4H (0.64) | LTA4HKMT2APOLB | |
| SCHEMBL8716635 | 0.69 | CHEK2 (0.46) | CHEK2LTA4HMAPK1CYP1A2CYP3A4 | |
| SCHEMBL6016481 | 0.69 | ALDH1A1 (0.49) | MAPK1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3866051 | 0.69 | CHEK2 (0.56) | CHEK2LTA4HMAPK1KMT2A | |
| SCHEMBL7335065 | 0.69 | LTA4H (0.54) | CHEK2LTA4HKMT2A | |
| SCHEMBL6053346 | 0.69 | CHEK2 (0.58) | CHEK2LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073279-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-07 | — | — | WO | disclosed |