Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017539 | 0.90 | NPC1 (0.34) | LTA4HEPHX2LMNA | |
| SCHEMBL4192274 | 0.86 | NPC1 (0.31) | — | |
| SCHEMBL4191147 | 0.85 | RAB9A (0.39) | LTA4HEPHX2LMNA | |
| SCHEMBL4194901 | 0.85 | LTA4H (0.38) | LTA4HEPHX2LMNAGAA | |
| SCHEMBL4190183 | 0.83 | MAPT (0.40) | LMNAGAAHPGD | |
| SCHEMBL4192264 | 0.81 | LMNA (0.40) | LTA4HEPHX2LMNAHPGD | |
| SCHEMBL4190204 | 0.80 | MAPT (0.37) | LMNA | |
| SCHEMBL4192472 | 0.80 | NPC1 (0.46) | LMNA | |
| SCHEMBL4186370 | 0.79 | RAB9A (0.42) | LMNAHPGDACP1 | |
| SCHEMBL7701894 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |