⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704487 | 0.79 | LTA4H (0.36) | — | |
| SCHEMBL7707674 | 0.78 | — | — | |
| SCHEMBL6017539 | 0.76 | NPC1 (0.34) | — | |
| SCHEMBL4192274 | 0.72 | NPC1 (0.31) | — | |
| SCHEMBL4191147 | 0.71 | RAB9A (0.39) | — | |
| SCHEMBL4194901 | 0.71 | LTA4H (0.38) | — | |
| SCHEMBL4190281 | 0.69 | ALDH1A1 (0.40) | — | |
| SCHEMBL4192264 | 0.69 | LMNA (0.40) | — | |
| SCHEMBL7707445 | 0.69 | MAPK10 (0.33) | — | |
| SCHEMBL7707034 | 0.67 | MAPK10 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |