Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396523 | 0.91 | ILK (0.41) | POLBALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL7393436 | 0.88 | ILK (0.44) | IRAK4ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL5596770 | 0.88 | SMN1; SMN2 (0.46) | IRAK4ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL5596381 | 0.83 | TSHR (0.41) | POLBALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL5103679 | 0.80 | IRAK4 (0.46) | IRAK4AURKAFLT4POLBMGLL | |
| SCHEMBL5042890 | 0.78 | MAPK9 (0.46) | AURKAFLT4POLBALDH1A1TSHR | |
| SCHEMBL5103637 | 0.76 | ALDH1A1 (0.46) | POLBALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL5596710 | 0.76 | ALDH1A1 (0.47) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5975398 | 0.73 | IRAK4 (0.37) | IRAK4ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL4950093 | 0.73 | LTA4H (0.50) | POLBALDH1A1RAB9ASMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |