Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396523 | 0.91 | ILK (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1ILK | |
| SCHEMBL7393436 | 0.88 | ILK (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1ILK | |
| SCHEMBL7704510 | 0.88 | HTR3A (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5596381 | 0.83 | TSHR (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4950093 | 0.81 | LTA4H (0.50) | SMN1; SMN2RAB9AGHSRHCAR1ALDH1A1 | |
| SCHEMBL4952153 | 0.76 | MAPK8 (0.49) | SMN1; SMN2RAB9AGHSRHCAR1ALDH1A1 | |
| SCHEMBL5596710 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL5103637 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1ILK | |
| SCHEMBL5975398 | 0.73 | IRAK4 (0.37) | SMN1; SMN2ALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL14921310 | 0.72 | IRAK4 (0.61) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |