Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.49 |
| ▸ | ILK | Q13418 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952153 | 0.84 | MAPK8 (0.49) | LTA4HILKALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL5596770 | 0.81 | SMN1; SMN2 (0.46) | ILKUSP2GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5596710 | 0.78 | ALDH1A1 (0.47) | ILKGAAALDH1A1SMN1; SMN2MAPK9 | |
| SCHEMBL5033422 | 0.78 | MAPK9 (0.47) | LTA4HGAAALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL5042890 | 0.77 | MAPK9 (0.46) | LTA4HILKGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4946974 | 0.76 | ALDH1A1 (0.40) | ILKGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4949154 | 0.76 | MKNK1 (0.47) | MKNK1ILKGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4949235 | 0.75 | RAB9A (0.44) | LTA4HGAAALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL5033477 | 0.74 | MAPK9 (0.45) | LTA4HGAAALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL5596354 | 0.74 | SMN1; SMN2 (0.50) | GAAALDH1A1SMN1; SMN2MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | disclosed |