Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698703 | 0.81 | SLC6A9 (0.59) | PPARDPPARAFFAR1SLC6A9TACR1 | |
| Lithium Ion SCHEMBL7702956 | 0.77 | SLC6A9 (0.49) | RORCFFAR1SLC6A9TACR1TRPV1 | |
| SCHEMBL7699247 | 0.76 | MTNR1A (0.53) | PPARDPPARAMTNR1AMTNR1BFFAR1 | |
| Hydrochloric Acid SCHEMBL7701267 | 0.75 | MTNR1A (0.49) | PPARDPPARAMTNR1AMTNR1BFFAR1 | |
| Hydrochloric Acid SCHEMBL7706012 | 0.74 | MTNR1A (0.65) | MTNR1AMTNR1BSLC6A9 | |
| SCHEMBL31757157 | 0.74 | SLC6A9 (0.69) | PPARDPPARAMTNR1AMTNR1BSLC6A9 | |
| SCHEMBL7698390 | 0.74 | SLC6A9 (0.55) | PPARDPPARAMTNR1AMTNR1BSLC6A9 | |
| SCHEMBL7706108 | 0.74 | SLC6A9 (0.69) | PPARDPPARAMTNR1AMTNR1BSLC6A9 | |
| Hydrochloric Acid SCHEMBL7706179 | 0.73 | MTNR1A (0.47) | PPARDPPARAMTNR1AMTNR1BFFAR1 | |
| SCHEMBL7700515 | 0.73 | SLC6A9 (0.49) | PPARDPPARARORCFFAR1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |