Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703728 | 0.81 | NR1H2 (0.38) | KLK7MEN1KMT2A | |
| SCHEMBL7697794 | 0.77 | KLK7 (0.39) | KLK7MEN1KMT2A | |
| SCHEMBL7697791 | 0.77 | KLK7 (0.39) | KLK7MEN1KMT2A | |
| SCHEMBL5065670 | 0.74 | KLK7 (0.49) | KLK7MEN1KMT2A | |
| SCHEMBL31486428 | 0.74 | KLK7 (0.49) | KLK7MEN1KMT2A | |
| SCHEMBL8669568 | 0.74 | KLK7 (0.49) | KLK7MEN1KMT2A | |
| SCHEMBL4626477 | 0.72 | POLB (0.52) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL6494880 | 0.71 | KLK7 (0.36) | KLK7 | |
| SCHEMBL7703661 | 0.71 | AGTR2 (0.38) | KLK7 | |
| SCHEMBL7703658 | 0.71 | AGTR2 (0.38) | KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |