Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704963 | 0.90 | CYP3A4 (0.34) | — | |
| SCHEMBL7704909 | 0.90 | MMP8 (0.31) | SMN1; SMN2 | |
| SCHEMBL7711245 | 0.89 | LTB4R (0.33) | POLBSMN1; SMN2RIPK1 | |
| SCHEMBL7711358 | 0.89 | ACE2 (0.34) | MAOBKDM4E | |
| SCHEMBL7704869 | 0.89 | GRM2 (0.33) | KDM4E | |
| SCHEMBL7711454 | 0.88 | FDPS (0.32) | — | |
| SCHEMBL7711363 | 0.87 | EPHX2 (0.30) | — | |
| SCHEMBL7711183 | 0.86 | NR3C2 (0.40) | POLBMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL7708186 | 0.86 | — | — | |
| SCHEMBL7708017 | 0.86 | IDO1 (0.33) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |