Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715200 | 0.71 | MKNK1 (0.37) | — | |
| SCHEMBL7710613 | 0.70 | CYP11B1 (0.38) | — | |
| SCHEMBL7712670 | 0.69 | ERN1 (0.34) | — | |
| SCHEMBL7712995 | 0.68 | BACE1 (0.41) | — | |
| SCHEMBL7710882 | 0.68 | CCNC (0.38) | — | |
| SCHEMBL2707237 | 0.61 | LMNA (0.43) | TYR | |
| SCHEMBL28500240 | 0.59 | RNASEH1 (0.45) | TYR | |
| SCHEMBL7785869 | 0.59 | GAA (0.36) | TYR | |
| SCHEMBL7778988 | 0.59 | PTPN1 (0.38) | TYR | |
| SCHEMBL9062904 | 0.57 | KCNE1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |