Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.35 |
| ▸ | CTSD | P07339 | 8/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705409 | 0.88 | BACE1 (0.45) | BACE1CTSDDHODHKCNH2 | |
| SCHEMBL7705399 | 0.84 | BACE1 (0.35) | BACE1CTSD | |
| SCHEMBL7709563 | 0.79 | MKNK1 (0.35) | BACE1CTSD | |
| SCHEMBL7713517 | 0.74 | CTSD (0.32) | BACE1CTSD | |
| SCHEMBL10266284 | 0.74 | BACE1 (0.38) | BACE1CTSD | |
| SCHEMBL882562 | 0.74 | BACE1 (0.46) | BACE1CTSD | |
| SCHEMBL10266269 | 0.73 | BACE1 (0.37) | BACE1CTSD | |
| SCHEMBL7708344 | 0.73 | ERN1 (0.32) | BACE1KCNH2 | |
| SCHEMBL7713121 | 0.72 | BACE1 (0.38) | BACE1CTSDKCNH2 | |
| SCHEMBL7710843 | 0.71 | HTR2C (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |