Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477272 | 0.77 | F2 (0.30) | F2 | |
| SCHEMBL6484948 | 0.74 | DPP4 (0.40) | L3MBTL1DGAT1ALDH1A1 | |
| SCHEMBL8723763 | 0.70 | PRSS1 (0.42) | F2L3MBTL1DGAT1PRSS1TMPRSS15 | |
| SCHEMBL7702747 | 0.68 | DGAT1 (0.39) | F2DGAT1PRSS1TMPRSS15OPRM1 | |
| Proline SCHEMBL8727242 | 0.68 | NOS2 (0.39) | F2ITGB3ITGA2BGRM5 | |
| Acetic Acid SCHEMBL6476505 | 0.66 | NNMT (0.50) | L3MBTL1GRM5 | |
| SCHEMBL6476554 | 0.66 | NNMT (0.57) | L3MBTL1GRM5 | |
| SCHEMBL6484032 | 0.66 | PRSS1 (0.38) | F2DGAT1PRSS1TMPRSS15ALDH1A1 | |
| SCHEMBL8725887 | 0.66 | F2 (0.40) | F2PRSS1OPRM1 | |
| SCHEMBL8722619 | 0.66 | F2 (0.40) | F2DGAT1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444817-B1 | ANTICOAGULANTS | ABBOTT LABORATORIES | 2002-09-03 | — | — | US | disclosed |
| US-6030972-A | 2- OR 5-AMINOMETHYL,2- OR 5-CYANOPYRIMIDINES AS INTERMEDIATES OF ANTICOAGULANTS IN EXTRACORPOREAL CIRCULATION (HEART-LUNG MACHINE, HEMODIALYSIS) | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |