Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476434 | 0.82 | OPRM1 (0.46) | PRSS1TMPRSS15F2ALDH1A1ACE | |
| SCHEMBL6484032 | 0.81 | PRSS1 (0.38) | PRSS1TMPRSS15F2ALDH1A1NPSR1 | |
| SCHEMBL6484948 | 0.78 | DPP4 (0.40) | ALDH1A1CA2DGAT1L3MBTL1 | |
| SCHEMBL8933085 | 0.78 | HSD11B1 (0.40) | PRSS1TMPRSS15F2ALDH1A1ACE | |
| SCHEMBL29405754 | 0.77 | ACE (0.56) | F2ACEREN | |
| SCHEMBL29380436 | 0.77 | ACE (0.56) | F2ACEREN | |
| SCHEMBL6681470 | 0.74 | ACE (0.51) | F2ACEREN | |
| SCHEMBL30899064 | 0.74 | ACE (0.51) | F2ACEREN | |
| SCHEMBL6681472 | 0.74 | ACE (0.51) | F2ACEREN | |
| SCHEMBL7702747 | 0.74 | DGAT1 (0.39) | PRSS1TMPRSS15F2ALDH1A1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |