SCHEMBL7705803

SCHEMBL7705803

C=Cc1ccccc1CC(=O)OC1C2CC3CC(C2)CC1C3

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 8/20 0.38
EPHX2 P34913 3/20 0.34
CTSV O60911 1/20 0.33
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
CCKBR P32239 2/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7703171 0.81 CYP19A1 (0.54) CTSVCTSLCTSSCTSKCYP19A1
SCHEMBL1397178 0.80 PTGDR2 (0.40) HSD11B1
SCHEMBL1397070 0.77 EPHX2 (0.39) HSD11B1EPHX2CTSVCTSLCTSS
SCHEMBL2194806 0.75 HSD11B1 (0.36) HSD11B1EPHX2CTSVCTSLCTSS
SCHEMBL1738983 0.72 CYP3A4 (0.36)
SCHEMBL5283277 0.72 KDM4E (0.43)
SCHEMBL4443824 0.69 ALDH1A1 (0.40)
SCHEMBL6708734 0.69 MGLL (0.54)
SCHEMBL21295985 0.69 MTNR1A (0.44)
SCHEMBL27834863 0.68 CNR2 (0.39) HSD11B1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1248150-A2 Radiation sensitive material and method for forming pattern FUJITSU LIMITED (JP) 2002-10-09 EP disclosed
EP-0663616-A2 Radiation sensitive material and method for forming pattern FUJITSU LIMITED (JP) 1995-07-19 EP disclosed