Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 11/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705969 | 0.86 | MAPT (0.52) | FYNMEN1ABCB1KMT2AABCG2 | |
| SCHEMBL7709149 | 0.84 | FYN (0.46) | FYNMAPT | |
| SCHEMBL7708573 | 0.81 | ADORA2A (0.52) | ADORA2AMEN1KMT2AADORA3TP53 | |
| SCHEMBL7709150 | 0.81 | ADORA2A (0.54) | FYNADORA2AMEN1KMT2AADORA3 | |
| SCHEMBL7484739 | 0.80 | ADORA2A (0.52) | ADORA2AADORA3HSD17B10 | |
| SCHEMBL7705893 | 0.80 | ADORA2A (0.52) | FYNADORA2ATP53KDM4ENPC1 | |
| SCHEMBL7481934 | 0.80 | ADORA2A (0.54) | FYNADORA2ATP53KDM4ENPC1 | |
| SCHEMBL7708431 | 0.80 | POLB (0.43) | FYNTP53KDM4EALDH1A1MAPT | |
| SCHEMBL7708740 | 0.80 | ADORA2A (0.57) | FYNADORA2AMEN1KMT2AADORA3 | |
| SCHEMBL7708503 | 0.79 | NPC1 (0.53) | FYNADORA2AMEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |