Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705875 | 0.90 | TP53 (0.42) | FYNPOLBMAPTTDP1 | |
| SCHEMBL7705871 | 0.84 | FYN (0.55) | FYNMAPT | |
| SCHEMBL7705877 | 0.83 | SMN1; SMN2 (0.41) | MAPT | |
| SCHEMBL7708772 | 0.82 | SMN1; SMN2 (0.38) | FYNPOLBMAPT | |
| SCHEMBL7705969 | 0.82 | MAPT (0.52) | FYNPOLBMAPT | |
| SCHEMBL7711838 | 0.80 | SMN1; SMN2 (0.50) | POLBMAPT | |
| SCHEMBL7708546 | 0.77 | NPC1 (0.42) | BRAFMAPT | |
| SCHEMBL7711818 | 0.77 | ALDH1A1 (0.42) | POLBMAPT | |
| SCHEMBL7705893 | 0.77 | ADORA2A (0.52) | FYNMAPT | |
| SCHEMBL7484739 | 0.77 | ADORA2A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |